First trimester screening, OSCAR) Olomouc, Ostrava - Ultrasound examination Ostrava, Olomouc - Ishraq Dhaifalah - Centre of Fetal Medicine and Human Genetics Ostrava, Olomouc Ishraq Dhaifalah - Centre of Fetal Medicine and Human Genetics Ostrava, Olomouc


First trimester screening - OSCAR (one stop clinic) - 11th -13th week gestation

The period between 11th and 13+6th week of gestation is ideal for so called first trimester screening (see also 1.6 chromosomal abnormality screening). The purpose of this examination is to establish the risk of a chromosomal abnormality in the fetus and to exclude some structural abnormalities in the fetus. The commonest chromosomal abnormality is Down syndrome (trisomy 21); other relatively common ones are Edwards’s syndrome (trisomy 18) and Patau syndrome (triosmy 13). Down syndrome is present in about 1 in 800 pregnancies; Edwards and Patau syndrome are much rarer. The risk is generally lower in younger women; it increases sharply with advancing age.

The investigation consists of a blood test of the mother and an ultrasound investigation of the fetus. The risk is then calculated using of sophisticated software and the result is usually available during the same day.

OSCAR (One Stop Clinic)

OSCAR is a concept of first trimester screening which allows the whole testing process to be completed within a few hours. It consists of blood analysis, ultrasound examination of the fetus and an integration of these factors using a computer program. This determines the individual risk for the commonest chromosomal abnormalities in the fetus. When the risk is above a predetermined level the situation is explained to the pregnant woman in detail and an invasive test such as chorionic villus sampling or amniocentesis is offered. The sample is evaluated using the most advanced methods such as FISH or PCR which allows us to issue final results within two or three days of the test.

We use the most advanced technology to perform the detailed ultrasound examination which provides the best opportunity to view the fetus. During the screening examination we evaluate the global morphology of the fetus and investigate in detail musculoskeletal system, central nervous system, digestive tract, heart, urinary tract, placenta and amniotic fluid. Then we examine the markers of chromosomal aberrations. The most important is a nuchal translucency (NT), which we measure according to international standards.

Normal values of nuchal translucency decrease the risk of a chromosomal and a heart abnormality in the fetus. If the value of NT is increased we perform further tests. We also examine nasal bone (NB), the presence of which decreases the risk of a chromosomal abnormality threefold, blood flow through the tricuspidal valve of the heart (tricuspidal regurgitation), blood flow through a venous connection called ductus venosus (DV) and we measure frontomaxilar angle (FMA).

We are also able to examine intracranial translucency, which is a structure in the region of the brainstem - this helps indirectly to exclude neural tube defects (spina bifida) in the first trimester.

The examination is usually preformed with transabdominal probe; we use a vaginal probe only in case of poor visibility. An advantageous examination is the use of 3D technology, which helps us in cases of some rarer abnormalities.

FETMED s.r.o.

FacebookOSTRAVA - Dr. Martínka 7, 700 30 Ostrava – Hrabůvka, Czech Republic
tel.: +420 773 190 249,

OLOMOUC - Horní Lán 1200/13, 779 00 Olomouc, Czech Republic
tel.: +420 605 825 780,

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